Posted on November 11, 2022 by Munchies

As interest in cannabinoids grows, HHCP, or Hexahydrocannabiphorol, has captured the attention of both researchers and users. Often compared to THC, HHCP is gaining attention for its intense potency and the unique experience it provides. But what exactly is HHCP, and how does it differ from other cannabinoids? In this article, we’ll discover everything you need to know about this cannabinoid. 

Key Takeaways

  • The high from HHCP typically lasts several hours, and the effects vary depending on individual factors and the method of consumption.​
  • HHCP is 10 to 20 times stronger than the staple THC, but human receptors can only feel 3 to 5 times its intensity. 
  • HHCP can be produced through hydrogenating either HHC or THCP. 
  • There are general dosage guidelines based on body weight or method of consumption, but it’s always a priority to consult with a medical professional for your safety. 

What is HHCP? 

HHCP, which stands for Hexahydrocannabiphorol, is a cannabinoid that many consider to be one of the most significant among its counterparts. It is a synthetic compound, which means it is artificially created rather than extracted from cannabis plants. 

HHCP is synthesized through the hydrogenation of THCP, contributing to its characteristics and potency. Due to its chemical structure, HHCP has been noted for its highly potent psychoactive effects, making it distinct from other cannabinoids.

Chemical Structure of HHCP 

HHCP, which stands for Hexahydrocannabiphorol, is similar to the minor cannabinoid HHC (hexahydrocannabinol). Its chemical formula is C23H36O2, with a molecular weight of 344.5308 g/mol. HHCP is characterized by a 7-carbon side chain, distinguishing it from other cannabinoids.

The full chemical name of HHCP is

3-heptyl-6,6,9-trimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-1-ol. 

It has two known isomers, 9R-HHCP and 9S-HHCP, with different potencies regarding their interaction with CB1 receptors.

HHCP possesses a structure similar to that of tetrahydrocannabinol (THC). This structural similarity plays a role in its interactions with cannabinoid receptors in the body, potentially affecting its psychoactive properties. These receptors regulate body functions such as sleeping, mood swings, eating, and other vital roles. 

HHCP: Is it Natural or Synthetic? 

​HHCP, or Hexahydrocannabiphorol, is a synthetic cannabinoid, which means it is artificially created in a laboratory setting rather than being sourced from the cannabis plant.​ This distinction is crucial for understanding its origins and potential legal and regulatory implications. 

Natural cannabinoids, such as THC and CBD, occur naturally within the cannabis plant. In contrast, HHCP’s entire existence is contingent upon synthetic processes, highlighting its distinction from natural cannabinoids. The artificial nature of HHCP may affect considerations regarding its effects, legality, and safety.

Is HHCP Safe? 

HHCP is safe as long as it’s used responsibly. ​While preliminary reports suggest that HHCP may be relatively safe for adults, a lack of comprehensive and peer-reviewed research and regulation still urges users to exercise extra caution.​ 

HHCP is a relatively new compound in the cannabinoid market, and its safety profile is still under investigation. Users should be aware and responsible for the potential risks and uncertainties surrounding this synthetic cannabinoid.

Does HHCP Get You High? 

Yes. HHCP (Hexahydrocannabiphorol) can produce a “high” feeling for consumers. To support this, THCP, and HHCP’s parent compound and a derivative of THC, can induce a high. 

However, the precise nature and intensity of these effects are not fully understood due to limited research on this synthetic cannabinoid. Initial reports tell us that the potency of HHCP is around 10 to 20 times stronger than THC. While this is a piece of exciting news to seasoned cannabis users, our human receptors can only feel about 3 to 5 times its intensity.  

How Long Does A HHCP High Last? 

The high duration of HHCP varies among users but generally lasts several hours. Onset times may also vary based on the consumption mode, with some reports indicating effects can start within minutes and persist for up to six hours.

Duration of Effects

Reports suggest that the effects of HHCP can last from around 2 to 6 hours at maximum, depending on individual factors such as metabolism, tolerance level, dosage, usage frequency, and consumption methods.

Onset Time

The onset of HHCP effects typically occurs within a few to tens of minutes after consumption, depending on how the compound is administered. For example, inhalation methods such as vaping may lead to quicker onset compared to edibles (30 minutes to 2 hours), which require digestion.

How is HHCP Made? 

HHCP is produced through the hydrogenation of HHC or THCP. Here’s how its production process takes place: 

Hydrogenation Synthesis Process

HHCP is produced by a chemical process that first involves hydrogenation, wherein hydrogen atoms are added to the molecular structure of HHC. This process modifies the cannabinoid’s chemical structure, producing a more stable compound that contributes to its longer shelf life.

Molecular Transformation

Specifically, the synthesis begins with HHC oil, which undergoes a molecular transformation in a lab setting. By adding two carbon atoms to HHC’s molecular chain, chemists create the HHCP molecule. This step is crucial as it contributes to HHCP’s unique properties compared to other cannabinoids.

Using THCP as an Alternative 

Using a similar hydrogenation approach, HHCP can also be derived from THCP (Tetrahydrocannabiphorol). The process ensures that HHCP is a fully saturated compound, which means it contains no double bonds within its molecular framework.

Stability and Attributes

The hydrogenation process alters the molecular structure and enhances the stability of HHCP compared to its parent compounds. This stability gives it a longer shelf life, which is significant for various applications. Furthermore, it can influence the effects of the cannabinoid upon consumption.

Potential Uses for HHCP

HHCP (Hexahydrocannabiphorol) is a synthetic cannabinoid with potential for various therapeutic applications, although research is still limited. Its reported effects include pain management, stress relief, and improved sleep.

Pain Management

One of the most promising potential uses of HHCP is in pain management. The compound’s potency and analgesic properties make it a subject of interest for those seeking alternatives for pain relief. Its effectiveness in this area could rival that of Delta 9 THC.

Anti-Inflammatory Effects

Beyond pain relief, HHCP has shown potential anti-inflammatory solid capabilities. This property could make it helpful in treating conditions characterized by inflammation, although more research is needed to fully understand its efficacy and mechanisms of action.

Stress and Anxiety Relief

Users have reported experiencing stress relief and relaxation when using HHCP. This suggests that the compound may have potential applications in managing anxiety and stress-related disorders.

Sleep Improvement

Another reported benefit of HHCP is improved sleep. This could make it a potential option for individuals struggling with sleeping troubles, although more clinical studies are needed to confirm its efficacy and safety.

Appetite Stimulation or “The Munchies” 

HHCP has been associated with increased appetite, commonly known as “the munchies” effect. This effect could benefit individuals experiencing appetite loss due to medical conditions or treatments.

Mood Enhancement

Users have reported experiencing euphoria and mood elevation when using HHCP. While this suggests potential mood-enhancing properties, it’s important to note that more research is needed to understand the full implications of these effects.

Nausea Relief

Some sources suggest that HHCP might help with nausea. This could make it potentially useful for individuals undergoing treatments that cause nausea as a side effect, such as chemotherapy.

While these potential uses can be exciting to users, it’s still important to note that research on HHCP is still in its infancy. The compound’s synthetic nature and potency necessitate careful consideration of its safety profile and potential risks. Additionally, the legal status of HHCP varies by jurisdiction, which may affect its availability and use.

Potential Risks of Using HHCP

While HHCP appears to be generally well-tolerated in mild to moderate doses, its use is associated with some risks and concerns.

 Some potential side effects reported include:

  • Anxiety
  • Paranoia
  • Dizziness
  • Dry mouth
  • Red eyes

It’s important to note that these side effects are similar to those associated with high THC doses, and they are usually temporary.

Someone opening their hands, presenting cannabis nugs.

Pexels Photo by Alexander Grey

HHCP Consumption Methods 

Consuming HHCP can be done through various methods, similar to THC, THCP, and other cannabinoids. 

  • Vaping –  Involves using vape cartridges or pens to inhale HHCP vapor. Vaping typically provides rapid and potent effects, making it a preferred choice for many users. 
  • Edibles – HHCP-infused edibles, such as gummies, chocolates, and other food products, offer a discreet, longer-lasting consumption method. 
  • Tinctures and Oils –  These liquid preparations can be consumed by letting the mixture melt under the tongue for faster absorption or mixed into beverages. 
  • Concentrates – These are typically consumed through dabbing, which involves heating the concentrate and inhaling the vapor. 
  • Capsules – Similar to edibles, HHCP capsules provide a measured dose and typically have a delayed onset of effects.
  • Topicals – These products are primarily used for potential pain relief and are not typically associated with systemic effects or the “high” produced by other consumption methods.

HHCP Legality

HHCP is federally legal under the 2018 Farm Bill, provided they are produced from legal hemp and contain less than 0.3% THC. 

View the entire disclosure of the 2018 Farm Bill 

Several factors contribute to the varying legal status of HHCP across states:

  • Interpretation of the 2018 Farm Bill
  • State-specific hemp and cannabis laws
  • Classification of HHCP as a THC parent compound
  • Ongoing legislative discussions and evolving regulations

The legality of HHCP varies significantly at the state level. Given the evolving nature of cannabis regulations and the ongoing research into cannabinoids, the legal status of HHCP may be subject to change. Its synthetic nature and potency could potentially influence future regulatory decisions.

Find out if HHCP is legal in your state 

General Dosage Guidelines 

Due to limited research, HHCP (Hexahydrocannabiphorol) dosage guidelines must be well-established. However, based on available information, it’s generally recommended to start with a low dose and gradually increase as needed. 

The appropriate dosage can vary widely depending on individual tolerance, weight, and desired effects.

  • Starting Dose -For beginners or those with low tolerance, it’s advisable to start with a very low dose of HHCP, typically around 1-5mg. This allows users to gauge their sensitivity to the compound and minimize the risk of adverse effects.
  • Standard and Experienced Users – Standard users with some tolerance may consider doses in the range of 15-30mg. More experienced users or those with higher tolerance might use 30-60 mg or more doses. However, it’s crucial to note that these are general guidelines, so it’s important to prioritize your safety first by consulting with a medical professional.   

Dosage Forms and Methods

The appropriate dosage can vary depending on the consumption method:

  • For edibles –  Starting with 5-10mg is often recommended for new users.
  • With vaping or other inhalation methods –  Users might start with one or two small puffs and wait to assess the effects before consuming more.

Body Weight Considerations

Some sources suggest calculating HHCP dosage based on body weight:

  • Low-strength dose – 0.05 x body weight in pounds
  • Medium-strength dose – 0.1 x body weight in pounds
  • High-strength dose – 0.2 x body weight in pounds

Specific Use Cases

Dosage recommendations may vary based on the intended use:

  • For sleep –  A low-strength dose of 0.5mg HHCP per 10 pounds of body weight is suggested for sleep.
  • For pain relief – A medium-strength dose of 1mg HHCP per 10 pounds of body weight is recommended.
  • For recreational use – Starting with a low-strength dose and adjusting as needed is advised.

Cautions and Considerations

It’s important to note that HHCP strength is reportedly more potent than many other cannabinoids, including Delta 9 and Delta 8. This higher potency means that lower doses may produce stronger effects.

Currently, there are no officially established guidelines for safe HHCP consumption. The limited research on HHCP means that long-term effects and optimal dosages still need to be better understood.

​While these dosage guidelines provide a general framework, they should be cautiously followed.​ It’s crucial to start with low doses and carefully monitor individual responses. Remember to consult with a healthcare professional before using HHCP, especially for those with pre-existing health conditions or taking medications, is strongly recommended.

HHCP vs. Delta 9 THC Comparison Recap

While HHCP can cause high, its potency relative to other cannabinoids like Delta 9  is still a subject of more future studies. Some sources suggest that HHCP’s potency is comparable to THCP, which is considered one of the most potent minor cannabinoids on the market. 

Here’s a comprehensive comparison between the HHCP and Delta 9: 

Chemical Structure and Origin

HHCP

  • Chemical structure – Hydrogenated counterpart of HHC with a 7-carbon side chain
  • Origin – Semi-synthetic, derived from hemp through a multi-step process

Delta 9 THC

  • Chemical structure – 5-carbon atom side chain
  • Origin – Naturally occurring in cannabis plants

Potency and Effects

HHCP

  • Potency – Significantly more potent than Delta 9 THC, possibly 10-20 times stronger
  • Effects – Users report intense euphoria and long-lasting highs
  • Duration – Extended period of effects compared to Delta 9 THC

Delta 9 THC

  • Potency – Considered the baseline for comparison. 
  • Effects – Well-known euphoric effects, altered perception, and heightened sensory experiences. 
  • Duration – Dependent on consumption method. 

Binding Affinity and Mechanism of Action

HHCP

  • Enhanced binding to CB1 receptors due to its 7-carbon side chain
  • May interact more strongly with the endocannabinoid system

Delta 9 THC

  • Binds to both CB1 and CB2 receptors in the endocannabinoid system
  • Well-understood mechanism of action. 

HHCP

  • Legal status varies per state
  • May be legal under the 2018 Farm Bill if derived from hemp and contains <0.3% THC

Delta 9 THC

  • Federally illegal (Schedule I controlled substance)
  • Legal for medical use in many states, and for recreational use in some

Availability and Product Forms

HHCP

  • Limited availability, mainly in specialized products
  • Common forms: Vape cartridges, gummies, tinctures, and flower

Delta 9 THC

  • Widely available in various cannabis products
  • Common forms: Flower, edibles, oils, tinctures, and vape products

Research and Safety Profile

HHCP

  • Limited research available
  • Safety profile not well-established
  • Potential for more intense side effects due to higher potency

Delta 9 THC

  • Extensively researched
  • Well-established safety profile and known side effects
  • Common side effects include anxiety, paranoia, and impaired cognition

Potential Therapeutic Applications

HHCP

  • Potential therapeutic applications not well-established
  • May offer similar benefits to THC, but with increased potency

Delta 9 THC

  • Recognized therapeutic applications for pain management, appetite stimulation, and nausea relief. 
  • FDA-approved for certain medical conditions. 

Metabolism and Drug Testing

HHCP

  • Metabolism not well-studied
  • May result in positive THC test, but more research is needed

Delta 9 THC

  • Well-understood metabolism
  • Metabolites are detectable in standard drug tests

User Experience and Dosage

HHCP

  • Users report more intense and longer-lasting effects
  • Dosage –  Start very low (e.g., 1-5mg) due to high potency

Delta 9 THC

  • Well-known user experiences documented
  • Dosage: Varies based on tolerance and consumption method, typically 5-20 mg for edibles

This table concisely compares these cannabinoids based on their chemical properties, potency, effects, legal status, and safety profiles.​ It’s important to note that studies on HHCP are still limited compared to Delta 9 THC, and individual experiences may vary. 

Final Thoughts 

​HHCP may offer various potential therapeutic applications; however, more comprehensive research is needed to fully understand its benefits, risks, and appropriate uses.​ As with any new compound, individuals considering HHCP should consult with healthcare professionals and be aware of the current limitations in our understanding of its effects. 

Users should remain aware of their own experience and adjust their consumption accordingly. As the research for HHCP continues, the possibility of understanding its safety profile and potential effects will be specified to help users make informed decisions regarding its use. 

(Disclaimer reminder: This article is not medical advice. It is based on anecdotal user experience alone. If you are thinking about incorporating cannabis (delta-8 THC, delta-9 THC, CBD, etc) into your medicinal routine, please consult a healthcare professional. Do not stop taking any prescribed medications without first consulting your doctor.)

Disclaimer: This article reflects the laws of the United States at the time it was written. Because cannabis laws in the United States are subject to change at any time, please make sure that you are always staying up to date on your federal, state, and local county’s cannabis laws. Additionally, we are NOT encouraging anyone to break the law––we are simply showing people ways to legally and discreetly bring their cannabis products along with them on their travels so that they may have access to those products when they reach their intended destination.

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