Posted on August 29, 2023 by Munchies

Have you ever sought the right balance between euphoria and relaxation? With so many emerging cannabinoids in the industry, it’s easy to get lost with new available options.  Enter HHCO. Users are getting recognition for this compound for its smooth and potent effects. What makes HHCO that impressive, and why are users turning to it for a more refined experience?

Key Takeaways 

  • Vape it, eat it, smoke it. HHCO can be consumed differently, each delivering a distinct onset time and effects based on your preference. 
  • According to multiple manufacturers, HHCO is 1.5 to 3 times more potent than its parent compound, HHC. 
  • Users report a euphoric high with enhanced relaxation, mood elevation, and sensory perception, often without significant anxiety or paranoia.
  • HHCO is a semi-synthetic cannabinoid made by adding an acetyl group to HHC, a naturally occurring minor cannabinoid in cannabis plants. 
  • While HHCO is federally legal under the 2018 Farm Bill, its legal status can vary by state and internationally, so consumers should check local regulations before purchasing or using HHCO products.

What is HHCO? 

HHCO is one of the newest minor cannabinoids from hemp that hit the cannabis market. It is created by adding an acetate group to HHC (hexahydrocannabinol), resulting in a compound that is more stable and exhibits similar effects to those of THC. This process strengthens its potency, making HHCO a notable option for consumers seeking psychoactive experiences beyond traditional cannabinoids like CBD.

HHCO, or HHCO acetate, is recognized as one of the notable minor cannabinoids budding from the hemp industry. The chemical creation of HHCO involves combining HHC molecules with acetic anhydride, a process called acetylation, which also parallels the production of other cannabinoids like THCO. This synthesis results in the acetate version of HHC, enhancing its properties and noticeable effects compared to its predecessor.

HHCO is often described as being approximately 1.5 to 3 times stronger than HHC, providing a more pronounced psychoactive effect. However, in terms of intensity, while HHCO enhances the effects of HHC, it does not reach the same level of high that Delta 9 THC provides.

Users report that HHCO can deliver a high that rivals some experiences associated with Delta 9 THC, but not to the same degree of intensity. Many find that HHCO offers relaxation and euphoric sensations similar to what THC offers but with potentially less cerebral fog and a more controlled experience. 

Is HHCO Natural or Synthetic? 

HHCO is not naturally found in the cannabis plant. This compound is created through chemical processes in laboratory settings. It is a semi-synthetic cannabinoid created by using HHC, which is a natural cannabinoid found in small, detectable amounts in the cannabis plant. The process involves adding an acetate group to HHC, resulting in HHCO. The classification is called semi-synthetic as it utilizes a natural material (HHC) and a synthetic process (addition of the acetyl group). 

How is HHCO Produced or Extracted? 

​HHCO (Hexahydrocannabinol-O-acetate) is produced through a chemical process that involves modifying HHC (Hexahydrocannabinol) by adding an acetyl group.​ This semi-synthetic cannabinoid is not directly extracted from cannabis plants but is synthesized in laboratory settings from HHC, which itself is derived from hemp.

Synthesis from HHC

HHCO is produced by undergoing a chemical reaction known as acetylation, where an acetyl group is added to HHC. This process increases the compound’s potency and stability, providing stronger psychoactive effects.

Chemical Modification 

Specifically, the reaction typically employs acetic anhydride, which reacts with HHC. The result is HHCO, characterized by a more stable structure than HHC, and an enhancement in its psychoactive properties.

Extraction of HHC as a Precursor

Before HHCO can be synthesized, HHC must be extracted from the cannabis plant; the extraction process for obtaining HHC typically includes any of these methods:

  • Solvent Extraction – This method utilizes solvents like ethanol or carbon dioxide to separate the cannabinoids from the raw plant material. The plant material is mixed with the solvent and evaporated, leaving behind a crude extract containing cannabinoids, including HHC.
  • Mechanical Separation – This alternative involves using mechanical force to separate the trichomes from the cannabis plant. Trichomes contain most cannabinoids, enabling the extraction of HHC through methods such as dry-sieving, ice-water separation, or rosin press.
  • Hydrogenation Process – Once CBD is extracted, it undergoes a chemical reaction called hydrogenation. This involves introducing hydrogen gas to the CBD or THC molecule in a controlled environment, often in the presence of a catalyst such as palladium or platinum. This step transforms CBD or THC into HHC by modifying its chemical structure, enhancing its stability, and making it suitable for consumption through vaping. 

Acetylation Process 

In the production of HHCO, the acetylation step occurs after HHC has been synthesized from hemp. The process involves reacting HHC with acetic anhydride, among other possible reagents, to induce the chemical modification. This step is central to converting HHC into HHCO, enhancing its psychoactive effects compared to its predecessor.

Quality Control Measures

Ensuring its safety and efficacy is paramount as HHCO is produced through chemical processes; good manufacturing practices include:

  • Purification Steps – Post-synthesis, HHCO undergoes purification to remove any by-products, impurities, or residual chemicals that may have been introduced during production.
  • Third-Party Testing – Many manufacturers subject HHCO to third-party testing to confirm its purity, potency, and safety before bringing the product to market. This step is essential to ensure consumer safety and compliance with legal regulations.
Cannabis plant with hints of purple hues.

Pexels Photo by Randy Wiggins

HHCO vs. THC: Potency Comparison 

Delta 9 THC is more potent than HHCO. HHCO is reported to be about 1.5 to 3 times more powerful than its precursor, HHC (Hexahydrocannabinol). Conversely, Delta 9 THC is regarded as one of the most potent cannabinoids available, yielding a significantly stronger high compared to both HHCO and other cannabinoids like Delta 8. Users have mentioned that while HHCO can deliver practical psychoactive effects, it generally does not reach the intensity of Delta 9. 

Will HHCO Get You High?

Yes. HHCO has the ability to give users a high experience. This cannabinoid is considered more potent than its precursor, HHC. It is estimated by manufacturers to be 3 times more potent than HHC, which means it can produce a stronger high than HHC. This increased potency is due to the acetylation process used in its production, which enhances its ability to cross the blood-brain barrier. 

Characteristics of HHCO High

Individual experiences may differ based on dosage, tolerance, and personal physiology. Also, since HHCO is synthesized from HHC, it is processed differently in the body, and the high experience can differ. 

Users often report that HHCO gives a euphoric high with noticeable effects of relaxation, mood enhancement, and potential pain relief. Some users describe the experience as more subtle and less intrusive than a THC high, without causing significant anxiety or paranoia. 

What Type of High is HHCO?

HHCO is leaning more towards Indica-like high effects. The classification of HHCO (Hexahydrocannabinol-O-acetate) as either sativa or indica is not straightforward, as these terms traditionally refer to cannabis plant types rather than specific cannabinoids. However, based on user reports and the effects of HHCO, it appears to produce a high that combines elements usually observed with both sativa and indica strains. 

What Does an HHCO High Feel Like?

An HHCO high is typically described as a potent, euphoric experience combining relaxation and mood elevation. Users often report a sense of calm, well-being, potential pain relief, and improved sleep. The potential effects can be more intense than those of HHC or Delta 8 THC but may be experienced as smoother and less anxiety-inducing than Delta 9 THC. 

You can feel more distinct sounds, feel more intense touch, and see more vibrant colors. When taken with higher doses, it can sometimes lead to a couch-locked effect. The high experience can differ based on dosage, consumption method, and your body’s response to the cannabinoid. 

HHCO Potential Effects 

It is important to note that the effects of HHCO can vary significantly among individuals. Factors such as the method of consumption, dosage, and personal tolerance levels play critical roles in determining the overall experience. Some users might find that they require a higher dose to achieve the desired effects, especially when compared to Delta 9 THC.

Relaxation and Calm

Many users report that HHCO provides significant relaxation for the body and mind. This calming effect is often sought after by those looking to alleviate stress and anxiety, contributing to its popularity as a cannabinoid.

Euphoria and Uplifted Mood

In addition to relaxation, HHCO is associated with euphoria and an elevated mood. Users frequently describe a deep sense of happiness and well-being, which enhances their overall experience. This uplifting quality makes HHCO enjoyable for social settings and recreational use.

Pain Relief

HHCO may also offer potential pain relief, similar to other cannabinoids. Many users have noted that it helps alleviate physical discomfort, making it a potential option for chronic pain or inflammation patients.

Sleep Improvement

Another commonly reported effect of HHCO is its potential to improve sleep quality. Some individuals use it as a sleep aid, finding that it helps them fall asleep more easily and enjoy a deeper rest.

Enhanced Sensory Perception

After consuming HHCO, users sometimes report heightened sensory experiences. This includes enhanced perception of sights, sounds, and even tastes, which can lead to a more immersive experience during activities like listening to music or enjoying food.

Sedation

For some users, HHCO may have a sedative effect, making them feel drowsy or deeply relaxed. This is likely due to its interaction with the endocannabinoid system, which regulates sleep, relaxation, and stress. Those seeking relief from insomnia or chronic pain might benefit from its calming, sleep-inducing properties. However, sedation could also be a downside for users looking to stay alert or active.

Altered Perception

Like other cannabinoids, HHCO can affect the perception of time, space, and surroundings. Users may feel like time is passing slower or faster than usual, and their sense of reality might become somewhat distorted. Depending on the situation and individual, this altered perception can be enjoyable or disorienting. It can also impair cognitive and motor functions, making it difficult to focus or perform tasks.

HHCO Potential Side Effects

  • Dry Mouth (Cottonmouth) – One of the most frequently reported side effects of HHCO consumption is dry mouth, also known as cottonmouth. This can cause discomfort and increased thirst but is usually considered a minor inconvenience.
  • Anxiety – Some users may experience increased anxiety after consuming HHCO. This can be mainly directed at individuals who are prone to anxiety or when taking higher doses.
  • Red Eyes – Redness of the eyes is another common side effect associated with HHCO use. This is due to the dilation of blood vessels in the eyes, a common effect of many cannabinoids.
  • Dizziness – Users may experience dizziness or lightheadedness, especially when consuming higher doses of HHCO or combining it with other substances.
  • Rapid Heartbeat – Some individuals report experiencing an increased heart rate or palpitations after using HHCO. This can be concerning for some users, particularly those with pre-existing cardiovascular conditions.
  • Paranoia – In some cases, particularly with higher doses, HHCO may induce feelings of paranoia or heightened anxiety. This effect can be distressing for users and may be more likely in those predisposed to anxiety or paranoid thoughts.
  • Insomnia – While some users report improved sleep with HHCO, others may experience difficulty falling asleep or staying asleep, especially if consumed close to bedtime.
  • Impaired Motor Skills – As with other psychoactive substances, HHCO can impair motor skills and reaction times. This makes it unsafe to operate vehicles or heavy machinery while under its influence.
  • Potential for Dependency – While research is limited, there is a potential for developing dependency with regular use of HHCO, as with other cannabinoids. Users should be aware of this risk, especially if using HHCO frequently.

How Long Does HHCO Take to Hit? 

The onset time of HHCO typically takes about 30 to 40 minutes to take effect when vaped and approximately 1 hour when ingested through edibles such as gummies or tinctures. The onset times can vary based on individual metabolism and consumption methods, but the general onset time is consistent across various sources. New users should start with a low dose and allow sufficient time to assess the initial impact before consuming more.

How Long Does an HHCO High Last? 

Once HHCO kicks in, its effects can last anywhere from 2 to 6 hours, depending on the dosage consumed and individual tolerance levels. Users report that smaller doses might produce shorter effects, while higher doses can extend the duration of the high. 

Is HHCO Safe? 

Some sources suggest that taking HHCO is generally safe in the short term, with no immediate severe risks, given that it is used responsibly. However, this assessment is based on limited user reports and not on rigorous scientific studies. This absence of comprehensive scientific data makes it challenging to definitively state whether HHCO is safe for consumption.

How Do You Consume HHCO?

HHCO can be consumed through various methods, with vaping and oral ingestion being the most common. Each consumption method offers distinct onset times, effect durations, and overall experiences. The choice of consumption method often depends on personal preference, desired effects, and individual needs.

Vaping 

Vaping is one of the most popular methods for consuming HHCO. It involves using a vaporizer or an HHCO vape pen to heat the concentrate, creating an inhalable vapor.

Pros

  • Rapid onset of effects (typically within 30-40 minutes)
  • Easy to control dosage
  • Discreet and portable

Cons

  • Potential lung irritation
  • Effects may not last as long as other methods

HHCO Edibles

HHCO can be incorporated into various edible products, such as gummies, chocolates, or baked goods.

Pros

  • Long-lasting effects (up to 6-8 hours)
  • Discreet consumption
  • No inhalation required

Cons

  • Slower onset of effects (typically 1-2 hours)
  • Dosage can be more challenging to control

HHCO Concentrates

HHCO concentrates are liquid extracts that can be melted under the tongue or added to food and beverages.

Pros

  • Relatively fast onset (15-45 minutes when melted under the tongue )
  • Easy to control dosage
  • Versatile (can be added to food or drinks)

Cons

  • Some users may not enjoy the taste
  • Effects may not last as long as edibles

HHCO Capsules or Softgels

HHCO can be encapsulated for oral consumption.

Pros

  • Precise dosing
  • Convenient and discreet
  • No taste or smell

Cons

  • Slower onset of effects (similar to edibles)
  • Less versatile than other methods

HHCO-infused Topicals

While less common, HHCO can be incorporated into topical products for localized application.

Pros

  • Targeted relief for specific areas
  • Non-psychoactive (doesn’t produce a “high”)
  • Easy to apply

Cons

  • Limited systemic effects
  • Maybe less potent than other methods

Dabbing

For experienced users, HHCO concentrates can be consumed through dabbing, which involves vaporizing a concentrated form of the compound.

Pros

  • Intense and immediate effects
  • Efficient consumption of high doses

Cons

  • Can be overwhelming for inexperienced users
  • Requires specialized equipment

HHCO Flower and Prerolls 

These are ready-to-smoke joints that typically contain ground flower and can be infused with additional HHCO oil for enhanced effects. 

Pros

  • They eliminate the need for users to roll their own joints, making them a popular choice for on-the-go consumption.
  • Pre-rolls come in measured doses, which can help users manage their intake more effectively.
  • Smoking flower and pre-rolls are felt relatively quickly, typically within minutes.

Cons:

  • May have dangerous byproducts from combustion

How Many MG of HHCO Should I Take?: General Dosage Guidelines 

Caution: These are all generic guidelines based on limited research. To ensure personal safety, consumers should seek professional advice from a medical professional. As with any new substance, taking HHCO should be approached with high caution, especially if you have any existing medical conditions. 

General Dosage Recommendations

Based on user tolerance levels, the following general dosage guidelines are suggested:

  • Beginners (low tolerance) – 5mg-12mg per use
  • Regular users (medium tolerance) – 12mg-30mg per use
  • Advanced users (high tolerance) – 30mg-60mg+ per use

Dosage by Consumption Method

Vaping

  • Threshold Dose – 1 small puff
  • Psychoactive Dose – 1-2 puffs
  • Very Psychoactive Dose – 3+ puffs

Tinctures

For a 30ml tincture with 1000mg HHCO:

  • Threshold Dose – 8.25mg (1/4 of a dropper)
  • Psychoactive Dose – 16.5mg (1/2 of a dropper)
  • Very Psychoactive Dose – 33mg (1 full dropper)

HHCO Gummies

  • Threshold Dose –  5mg
  • Psychoactive Dose – 6-15mg
  • Very Psychoactive Dose – 16mg+

Edibles Dosage

For those new to HHCO edibles:

  • Start with a modest dose of about 5 milligrams
  • Wait at least 30 minutes to 2 hours before considering additional doses
  • Seasoned users often find their sweet spot between 10-20 milligrams per session

Dabs

  • Threshold Dose – 1 small puff
  • Psychoactive Dose – 1-2 puffs
  • Very Psychoactive Dose – 3+ puffs

Capsules Dosage

  • Beginner – 5-10mg per capsule
  • Regular – 10-20mg per capsule
  • Advanced – 20-40mg per capsule

It’s crucial to start with a low dose and increase based on your body’s reactions. This approach helps minimize potential side effects so users can assess their ideal effects. 

Can HHCO Show on Drug Tests? 

Yes. There is a possibility of testing positive for substance use with HHCO.  While testing specifically for HHCO is uncommon, there is a strong likelihood that HHC and HHCO will trigger a positive drug test result due to their structural and metabolic similarities to THC. 

As a result, individuals who use HHCO may risk failing a drug test, particularly if they are subjected to a comprehensive screening that targets common cannabinoids. HHCO and THC both interact with the body’s endocannabinoid system and share similar metabolic pathways. Because of this, consuming HHCO could lead to the production of similar metabolites that drug tests are designed to identify. A drug test may not differentiate between these compounds, leading to a potential false positive for THC when HHCO is consumed. 

HHCO is considered federally legal under the 2018 Farm Bill, which allows hemp-derived cannabis products containing less than 0.3% Delta 9 THC to be produced, marketed, and consumed. However, legality can vary by state, as some have enacted laws that may directly ban or provide certain restrictions on psychoactive cannabinoids. Consumers should check local regulations before purchasing or using HHCO products. 

Check the Full Disclosure of the 2018 Farm Bill

Different countries have distinctive approaches to legalizing hemp-derived cannabinoids, including HHCO. The legal status can range from fully legal to strictly prohibited, with many nations falling somewhere in between these extremes.

The legal status of HHCO is subject to change as more research is conducted and as governments continue to refine their policies on cannabis-derived compounds. It’s crucial for users and businesses to stay informed about the latest legal developments in their respective countries.

Final Thoughts 

HHCO is positioned as a potent, semi-synthetic cannabinoid offering a distinct psychoactive effect that blends relaxation, euphoria, and sensory enhancement. Although not as intense as Delta 9 THC, based on some users, its stronger potency compared to HHC makes it a popular choice among users seeking a milder yet effective high. 

With diverse consumption methods available, from vaping to edibles, HHCO serves different preferences. However, as with all new cannabinoids, it’s crucial to be mindful of dosage, individual tolerance, and potential side effects. As research continues to develop on this cannabinoid, understanding HHCO’s full range of potential benefits and risks will become clearer.

(Disclaimer reminder: This article is not medical advice. It is based on anecdotal user experience alone. If you are thinking about incorporating cannabis (delta-8 THC, delta-9 THC, CBD, etc) into your medicinal routine, please consult a healthcare professional. Do not stop taking any prescribed medications without first consulting your doctor.)

Disclaimer: This article reflects the laws of the United States at the time it was written. Because cannabis laws in the United States laws are subject to change at any time, please make sure that you are always staying up to date on your federal, state, and local county’s cannabis laws. Additionally, we are NOT encouraging anyone to break the law––we are simply showing people ways to legally and discreetly bring their cannabis products along with them on their travels so that they may have access to those products when they reach their intended destination.

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